Sjogren Syndrome (Sicca syndrome)

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Chronic inflammatory and autoimmune disorder characterized by diminished lacrimal and salivary gland secretion (sicca complex). This is a disorder of the immune system identified by its two most common symptoms - dry eyes and a dry mouth. Sjogren's syndrome often accompanies other immune-system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first, resulting in decreased production of tears and saliva. Although people can develop Sjogren's syndrome at any age, most people are older than 40 at the time of diagnosis. The condition is much more common in women. Treatment focuses on relieving symptoms, which often subside with time. Sjögren's syndrome often is undiagnosed or misdiagnosed. The symptoms of Sjögren's syndrome may mimic those of menopause, drug side effects, allergies, or medical conditions such as lupus, rheumatoid arthritis, fibromyalgia, chronic fatigue syndrome, and multiple sclerosis. Because all symptoms are not always present at the same time and because Sjögren's can involve several body systems, physicians, eye care providers and dentists sometimes treat each symptom individually and do not recognize that a systemic disease is present. The average time from onset of symptoms to diagnosis is 6.5 years.


Laboratory Test Procedures:

dry eyes
dry mouth
vaginal dryness
difficulty swallowing
painful swallowing
joint aches
joint swelling
joint stiffness
swollen salivary glands
dry skin
skin rash

Rheumatoid Factor, titers
Nuclear Ab ANA Screen
Extractable Nuclear Antigen Antibodies
C-Reactive Protein (CRP)
ESR - Sed Rate
Lymphocyte %
Lymphocyte Absolute
Eosinophil %
Eosinophil Absolute
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All information on this page is intended for your general knowledge only and does not provide medical advice, diagnosis or treatment. See Additional Information